BDBM50191808 (S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-cyclopropyl-4-(4-phenylpiperidin-1-yl)butanamide::CHEMBL215759

SMILES: FC(F)(F)c1cc(CNC(=O)[C@@H](CCN2CCC(CC2)c2ccccc2)C2CC2)cc(c1)C(F)(F)F

InChI Key: InChIKey=VNMQSFGXHMQIMW-DEOSSOPVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191808   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50191808 ((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-cycloprop...) Show SMILES FC(F)(F)c1cc(CNC(=O)[C@@H](CCN2CCC(CC2)c2ccccc2)C2CC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C27H30F6N2O/c28-26(29,30)22-14-18(15-23(16-22)27(31,32)33)17-34-25(36)24(21-6-7-21)10-13-35-11-8-20(9-12-35)19-4-2-1-3-5-19/h1-5,14-16,20-21,24H,6-13,17H2,(H,34,36)/t24-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	285	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCP-1 from human CCR2b expressed in CHO cells				Bioorg Med Chem Lett 16: 4715-22 (2006) Article DOI: 10.1016/j.bmcl.2006.07.011 BindingDB Entry DOI: 10.7270/Q2JD4WDC
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50191808 ((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-cycloprop...) Show SMILES FC(F)(F)c1cc(CNC(=O)[C@@H](CCN2CCC(CC2)c2ccccc2)C2CC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C27H30F6N2O/c28-26(29,30)22-14-18(15-23(16-22)27(31,32)33)17-34-25(36)24(21-6-7-21)10-13-35-11-8-20(9-12-35)19-4-2-1-3-5-19/h1-5,14-16,20-21,24H,6-13,17H2,(H,34,36)/t24-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCP-1 from human CCR2b expressed in human monocyte cells				Bioorg Med Chem Lett 16: 4715-22 (2006) Article DOI: 10.1016/j.bmcl.2006.07.011 BindingDB Entry DOI: 10.7270/Q2JD4WDC
					More data for this Ligand-Target Pair