BDBM50191835 4-ethoxy-6-(4-(4-methyl-1H-imidazol-5-yl)piperidin-1-yl)-5-phenylpyrimidine::CHEMBL211922

SMILES: CCOc1ncnc(N2CCC(CC2)c2[nH]cnc2C)c1-c1ccccc1

InChI Key: InChIKey=XVJHCYVTUCYGCH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Homo sapiens (Human))	BDBM50191835 (4-ethoxy-6-(4-(4-methyl-1H-imidazol-5-yl)piperidin...) Show SMILES CCOc1ncnc(N2CCC(CC2)c2[nH]cnc2C)c1-c1ccccc1 Show InChI InChI=1S/C21H25N5O/c1-3-27-21-18(16-7-5-4-6-8-16)20(24-14-25-21)26-11-9-17(10-12-26)19-15(2)22-13-23-19/h4-8,13-14,17H,3,9-12H2,1-2H3,(H,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human NHE1 expressed in Ap1 cell line				Bioorg Med Chem Lett 16: 4796-9 (2006) Article DOI: 10.1016/j.bmcl.2006.06.077 BindingDB Entry DOI: 10.7270/Q2DN44P1
					More data for this Ligand-Target Pair