BDBM50191919 CHEMBL380301::N-(2-bromophenyl)-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine

SMILES: Brc1ccccc1Nc1nccc(n1)-c1c[nH]c2ncccc12

InChI Key: InChIKey=GDXJAAIAGCCGJP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3 (Homo sapiens (Human))	BDBM50191919 (CHEMBL380301 | N-(2-bromophenyl)-4-(1H-pyrrolo[2,3...) Show SMILES Brc1ccccc1Nc1nccc(n1)-c1c[nH]c2ncccc12 Show InChI InChI=1S/C17H12BrN5/c18-13-5-1-2-6-15(13)23-17-20-9-7-14(22-17)12-10-21-16-11(12)4-3-8-19-16/h1-10H,(H,19,21)(H,20,22,23)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclinB by Flashplate assay				Bioorg Med Chem Lett 16: 4818-21 (2006) Article DOI: 10.1016/j.bmcl.2006.06.073 BindingDB Entry DOI: 10.7270/Q2571BNM
					More data for this Ligand-Target Pair