BDBM50191940 CHEMBL1761587
SMILES: Oc1ccc(cc1)N1C(=O)CS\C1=N/N=C1\C(=O)Nc2ccc(F)cc12
InChI Key: InChIKey=BESARYKONNKDMP-FXBPSFAMSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (Homo sapiens (Human)) | BDBM50191940 (CHEMBL1761587) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
Myrexis, Inc. Curated by ChEMBL | Assay Description Competitive inhibition of recombinant TAK1-TAB1 assessed as [33P]gamma-ATP incorporation into substrate histone H1 peptide by filter plate assay | Bioorg Med Chem Lett 21: 1724-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.077 BindingDB Entry DOI: 10.7270/Q2988794 | |||||||||||
More data for this Ligand-Target Pair |