BDBM50191942 CHEMBL1761744

SMILES: CC(C)C1S\C(=N/N=C2\C(=O)Nc3ccc(Cl)cc23)N(C1=O)c1ccc(O)cc1

InChI Key: InChIKey=JVGJJXMJRSUNCP-GFMRDNFCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191942   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (Homo sapiens (Human))	BDBM50191942 (CHEMBL1761744) Show SMILES CC(C)C1S\C(=N/N=C2\C(=O)Nc3ccc(Cl)cc23)N(C1=O)c1ccc(O)cc1 Show InChI InChI=1S/C20H17ClN4O3S/c1-10(2)17-19(28)25(12-4-6-13(26)7-5-12)20(29-17)24-23-16-14-9-11(21)3-8-15(14)22-18(16)27/h3-10,17,26H,1-2H3,(H,22,23,27)/b24-20-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Myrexis, Inc. Curated by ChEMBL					Assay Description Competitive inhibition of recombinant TAK1-TAB1 assessed as [33P]gamma-ATP incorporation into substrate histone H1 peptide by filter plate assay				Bioorg Med Chem Lett 21: 1724-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.077 BindingDB Entry DOI: 10.7270/Q2988794
					More data for this Ligand-Target Pair