BDBM50192081 3-(2-cyclopentyl-1-oxo-2,3-dihydro-1H-isoindol-4-yl)-1H-quinoxalin-2-one::CHEMBL385070

SMILES: O=C1N(Cc2c1cccc2-c1nc2ccccc2[nH]c1=O)C1CCCC1

InChI Key: InChIKey=NCAKBPLCBZCYSN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192081   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM50192081 (3-(2-cyclopentyl-1-oxo-2,3-dihydro-1H-isoindol-4-y...) Show SMILES O=C1N(Cc2c1cccc2-c1nc2ccccc2[nH]c1=O)C1CCCC1 Show InChI InChI=1S/C21H19N3O2/c25-20-19(22-17-10-3-4-11-18(17)23-20)14-8-5-9-15-16(14)12-24(21(15)26)13-6-1-2-7-13/h3-5,8-11,13H,1-2,6-7,12H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CDK4				Bioorg Med Chem Lett 16: 5122-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.026 BindingDB Entry DOI: 10.7270/Q2K35VF0
					More data for this Ligand-Target Pair