BDBM50192087 CHEMBL215629::trans-5-(4-fluorobenzyl)-6-oxo-N-((S)-1-phenylethyl)morpholine-3-carboxamide

SMILES: C[C@H](NC(=O)[C@H]1COC(=O)[C@H](Cc2ccc(F)cc2)N1)c1ccccc1

InChI Key: InChIKey=XZWIODIVZSHQOA-DOPJRALCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50192087 (CHEMBL215629 | trans-5-(4-fluorobenzyl)-6-oxo-N-((...) Show SMILES C[C@H](NC(=O)[C@H]1COC(=O)[C@H](Cc2ccc(F)cc2)N1)c1ccccc1 Show InChI InChI=1S/C20H21FN2O3/c1-13(15-5-3-2-4-6-15)22-19(24)18-12-26-20(25)17(23-18)11-14-7-9-16(21)10-8-14/h2-10,13,17-18,23H,11-12H2,1H3,(H,22,24)/t13-,17-,18+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Ability to block calcium channel T type 3.1v expressed in HEK293 cells by whole cell patch clamp method				Bioorg Med Chem Lett 16: 5244-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.031 BindingDB Entry DOI: 10.7270/Q2N58KZV
					More data for this Ligand-Target Pair