BDBM50192200 2-chloro-N-(2-(3,5-dichloro-2-hydroxyphenyl)-1H-benzo[d]imidazol-5-yl)benzamide::CHEMBL386447

SMILES: Oc1c(Cl)cc(Cl)cc1-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1

InChI Key: InChIKey=CVOZHNOLAFROBK-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM50192200 (2-chloro-N-(2-(3,5-dichloro-2-hydroxyphenyl)-1H-be...) Show SMILES Oc1c(Cl)cc(Cl)cc1-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C20H12Cl3N3O2/c21-10-7-13(18(27)15(23)8-10)19-25-16-6-5-11(9-17(16)26-19)24-20(28)12-3-1-2-4-14(12)22/h1-9,27H,(H,24,28)(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells				Bioorg Med Chem Lett 16: 5001-4 (2006) Article DOI: 10.1016/j.bmcl.2006.07.056 BindingDB Entry DOI: 10.7270/Q280528D
					More data for this Ligand-Target Pair
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM50192200 (2-chloro-N-(2-(3,5-dichloro-2-hydroxyphenyl)-1H-be...) Show SMILES Oc1c(Cl)cc(Cl)cc1-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C20H12Cl3N3O2/c21-10-7-13(18(27)15(23)8-10)19-25-16-6-5-11(9-17(16)26-19)24-20(28)12-3-1-2-4-14(12)22/h1-9,27H,(H,24,28)(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at NR2E3 by beta lactamase transactivation assay				Bioorg Med Chem Lett 16: 5001-4 (2006) Article DOI: 10.1016/j.bmcl.2006.07.056 BindingDB Entry DOI: 10.7270/Q280528D
					More data for this Ligand-Target Pair