BDBM50192203 2-chloro-N-(4-(5-(2,2-difluorocyclopropanecarboxamido)-1H-benzo[d]imidazol-2-yl)phenyl)benzamide::CHEMBL214457

SMILES: FC1(F)CC1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1

InChI Key: InChIKey=YYBRDJACMSSFST-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM50192203 (2-chloro-N-(4-(5-(2,2-difluorocyclopropanecarboxam...) Show SMILES FC1(F)CC1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C24H17ClF2N4O2/c25-18-4-2-1-3-16(18)22(32)28-14-7-5-13(6-8-14)21-30-19-10-9-15(11-20(19)31-21)29-23(33)17-12-24(17,26)27/h1-11,17H,12H2,(H,28,32)(H,29,33)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at NR2E3 by beta lactamase transactivation assay				Bioorg Med Chem Lett 16: 5001-4 (2006) Article DOI: 10.1016/j.bmcl.2006.07.056 BindingDB Entry DOI: 10.7270/Q280528D
					More data for this Ligand-Target Pair
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM50192203 (2-chloro-N-(4-(5-(2,2-difluorocyclopropanecarboxam...) Show SMILES FC1(F)CC1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C24H17ClF2N4O2/c25-18-4-2-1-3-16(18)22(32)28-14-7-5-13(6-8-14)21-30-19-10-9-15(11-20(19)31-21)29-23(33)17-12-24(17,26)27/h1-11,17H,12H2,(H,28,32)(H,29,33)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells				Bioorg Med Chem Lett 16: 5001-4 (2006) Article DOI: 10.1016/j.bmcl.2006.07.056 BindingDB Entry DOI: 10.7270/Q280528D
					More data for this Ligand-Target Pair