BDBM50192212 2-chloro-N-(4-(5-(1-cyanocyclopropanecarboxamido)-1H-benzo[d]imidazol-2-yl)phenyl)benzamide::CHEMBL215498

SMILES: Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3(CC3)C#N)cc2[nH]1

InChI Key: InChIKey=HMLGLKCTOQYTPQ-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM50192212 (2-chloro-N-(4-(5-(1-cyanocyclopropanecarboxamido)-...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3(CC3)C#N)cc2[nH]1 Show InChI InChI=1S/C25H18ClN5O2/c26-19-4-2-1-3-18(19)23(32)28-16-7-5-15(6-8-16)22-30-20-10-9-17(13-21(20)31-22)29-24(33)25(14-27)11-12-25/h1-10,13H,11-12H2,(H,28,32)(H,29,33)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells				Bioorg Med Chem Lett 16: 5001-4 (2006) Article DOI: 10.1016/j.bmcl.2006.07.056 BindingDB Entry DOI: 10.7270/Q280528D
					More data for this Ligand-Target Pair
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM50192212 (2-chloro-N-(4-(5-(1-cyanocyclopropanecarboxamido)-...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3(CC3)C#N)cc2[nH]1 Show InChI InChI=1S/C25H18ClN5O2/c26-19-4-2-1-3-18(19)23(32)28-16-7-5-15(6-8-16)22-30-20-10-9-17(13-21(20)31-22)29-24(33)25(14-27)11-12-25/h1-10,13H,11-12H2,(H,28,32)(H,29,33)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at NR2E3 by beta lactamase transactivation assay				Bioorg Med Chem Lett 16: 5001-4 (2006) Article DOI: 10.1016/j.bmcl.2006.07.056 BindingDB Entry DOI: 10.7270/Q280528D
					More data for this Ligand-Target Pair