BDBM50192213 2-chloro-N-(2-(1-(4-fluorophenyl)-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-5-yl)benzamide::CHEMBL384066

SMILES: Fc1ccc(cc1)-n1cc(cn1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1

InChI Key: InChIKey=PEUHOGMONYOJND-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM50192213 (2-chloro-N-(2-(1-(4-fluorophenyl)-1H-pyrazol-4-yl)...) Show SMILES Fc1ccc(cc1)-n1cc(cn1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C23H15ClFN5O/c24-19-4-2-1-3-18(19)23(31)27-16-7-10-20-21(11-16)29-22(28-20)14-12-26-30(13-14)17-8-5-15(25)6-9-17/h1-13H,(H,27,31)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells				Bioorg Med Chem Lett 16: 5001-4 (2006) Article DOI: 10.1016/j.bmcl.2006.07.056 BindingDB Entry DOI: 10.7270/Q280528D
					More data for this Ligand-Target Pair
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM50192213 (2-chloro-N-(2-(1-(4-fluorophenyl)-1H-pyrazol-4-yl)...) Show SMILES Fc1ccc(cc1)-n1cc(cn1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C23H15ClFN5O/c24-19-4-2-1-3-18(19)23(31)27-16-7-10-20-21(11-16)29-22(28-20)14-12-26-30(13-14)17-8-5-15(25)6-9-17/h1-13H,(H,27,31)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at NR2E3 by beta lactamase transactivation assay				Bioorg Med Chem Lett 16: 5001-4 (2006) Article DOI: 10.1016/j.bmcl.2006.07.056 BindingDB Entry DOI: 10.7270/Q280528D
					More data for this Ligand-Target Pair