BDBM50192288 3-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3H-[1,2,3]triazole-4-carboxylic acid dimethylamide::CHEMBL214143

SMILES: CN(C)C(=O)c1cnnn1[C@@H]1O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]2(OS(=O)(=O)C=C2N)[C@H]1O[Si](C)(C)C(C)(C)C

InChI Key: InChIKey=LXRJTIDYGSKQHZ-RRZZWSPOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50192288 (3-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-si...) Show SMILES CN(C)C(=O)c1cnnn1[C@@H]1O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]2(OS(=O)(=O)C=C2N)[C@H]1O[Si](C)(C)C(C)(C)C |c:28| Show InChI InChI=1S/C24H45N5O7SSi2/c1-22(2,3)38(9,10)33-14-18-24(17(25)15-37(31,32)36-24)19(35-39(11,12)23(4,5)6)21(34-18)29-16(13-26-27-29)20(30)28(7)8/h13,15,18-19,21H,14,25H2,1-12H3/t18-,19+,21-,24-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh School of Medicine Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNA-dependent DNA polymerase activity				J Med Chem 49: 4834-41 (2006) Article DOI: 10.1021/jm0604575 BindingDB Entry DOI: 10.7270/Q2GH9HKC
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50192288 (3-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-si...) Show SMILES CN(C)C(=O)c1cnnn1[C@@H]1O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]2(OS(=O)(=O)C=C2N)[C@H]1O[Si](C)(C)C(C)(C)C |c:28| Show InChI InChI=1S/C24H45N5O7SSi2/c1-22(2,3)38(9,10)33-14-18-24(17(25)15-37(31,32)36-24)19(35-39(11,12)23(4,5)6)21(34-18)29-16(13-26-27-29)20(30)28(7)8/h13,15,18-19,21H,14,25H2,1-12H3/t18-,19+,21-,24-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh School of Medicine Curated by ChEMBL					Assay Description Inhibition of FLAG-p66/HIS-p51-mediated HIV1 reverse transcriptase dimerization				J Med Chem 49: 4834-41 (2006) Article DOI: 10.1021/jm0604575 BindingDB Entry DOI: 10.7270/Q2GH9HKC
					More data for this Ligand-Target Pair