BDBM50192292 (S)-2-(2-{3-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-acetylamino)-succinic acid::CHEMBL264069

SMILES: Cc1cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c(=O)n(CC(=O)N[C@@H](CC(O)=O)C(O)=O)c1=O

InChI Key: InChIKey=XZHULJGVKUMOSZ-MHOKIMLGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50192292 ((S)-2-(2-{3-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-d...) Show SMILES Cc1cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c(=O)n(CC(=O)N[C@@H](CC(O)=O)C(O)=O)c1=O |c:21| Show InChI InChI=1S/C30H50N4O13SSi2/c1-17-13-34(27(41)33(24(17)38)14-21(35)32-18(26(39)40)12-22(36)37)25-23(46-50(10,11)29(5,6)7)30(19(31)16-48(42,43)47-30)20(45-25)15-44-49(8,9)28(2,3)4/h13,16,18,20,23,25H,12,14-15,31H2,1-11H3,(H,32,35)(H,36,37)(H,39,40)/t18-,20+,23-,25+,30+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh School of Medicine Curated by ChEMBL					Assay Description Inhibition of FLAG-p66/HIS-p51-mediated HIV1 reverse transcriptase dimerization				J Med Chem 49: 4834-41 (2006) Article DOI: 10.1021/jm0604575 BindingDB Entry DOI: 10.7270/Q2GH9HKC
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50192292 ((S)-2-(2-{3-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-d...) Show SMILES Cc1cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c(=O)n(CC(=O)N[C@@H](CC(O)=O)C(O)=O)c1=O |c:21| Show InChI InChI=1S/C30H50N4O13SSi2/c1-17-13-34(27(41)33(24(17)38)14-21(35)32-18(26(39)40)12-22(36)37)25-23(46-50(10,11)29(5,6)7)30(19(31)16-48(42,43)47-30)20(45-25)15-44-49(8,9)28(2,3)4/h13,16,18,20,23,25H,12,14-15,31H2,1-11H3,(H,32,35)(H,36,37)(H,39,40)/t18-,20+,23-,25+,30+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh School of Medicine Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNA-dependent DNA polymerase activity				J Med Chem 49: 4834-41 (2006) Article DOI: 10.1021/jm0604575 BindingDB Entry DOI: 10.7270/Q2GH9HKC
					More data for this Ligand-Target Pair