BDBM50192307 3-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3H-[1,2,3]triazole-4-carboxylic acid amide::CHEMBL437717

SMILES: CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@]11OS(=O)(=O)C=C1N)n1nncc1C(N)=O

InChI Key: InChIKey=MJQIHSQWSVBLDS-ZRAXVTTISA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50192307 (3-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-si...) Show SMILES CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@]11OS(=O)(=O)C=C1N)n1nncc1C(N)=O |c:27| Show InChI InChI=1S/C22H41N5O7SSi2/c1-20(2,3)36(7,8)31-12-16-22(15(23)13-35(29,30)34-22)17(33-37(9,10)21(4,5)6)19(32-16)27-14(18(24)28)11-25-26-27/h11,13,16-17,19H,12,23H2,1-10H3,(H2,24,28)/t16-,17+,19-,22-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh School of Medicine Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase RNA-dependent DNA polymerase activity				J Med Chem 49: 4834-41 (2006) Article DOI: 10.1021/jm0604575 BindingDB Entry DOI: 10.7270/Q2GH9HKC
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50192307 (3-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-si...) Show SMILES CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@]11OS(=O)(=O)C=C1N)n1nncc1C(N)=O |c:27| Show InChI InChI=1S/C22H41N5O7SSi2/c1-20(2,3)36(7,8)31-12-16-22(15(23)13-35(29,30)34-22)17(33-37(9,10)21(4,5)6)19(32-16)27-14(18(24)28)11-25-26-27/h11,13,16-17,19H,12,23H2,1-10H3,(H2,24,28)/t16-,17+,19-,22-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh School of Medicine Curated by ChEMBL					Assay Description Inhibition of FLAG-p66/HIS-p51-mediated HIV1 reverse transcriptase dimerization				J Med Chem 49: 4834-41 (2006) Article DOI: 10.1021/jm0604575 BindingDB Entry DOI: 10.7270/Q2GH9HKC
					More data for this Ligand-Target Pair