BDBM50192515 CHEMBL384247::phenyl 2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenylcarbamate

SMILES: Cc1ccc(Oc2ccc(cc2NC(=O)Oc2ccccc2)C(=O)NCCN2CCCC2)cc1C

InChI Key: InChIKey=QAGQATKSRHKVBL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50192515 (CHEMBL384247 | phenyl 2-(3,4-dimethylphenoxy)-5-((...) Show SMILES Cc1ccc(Oc2ccc(cc2NC(=O)Oc2ccccc2)C(=O)NCCN2CCCC2)cc1C Show InChI InChI=1S/C28H31N3O4/c1-20-10-12-24(18-21(20)2)34-26-13-11-22(27(32)29-14-17-31-15-6-7-16-31)19-25(26)30-28(33)35-23-8-4-3-5-9-23/h3-5,8-13,18-19H,6-7,14-17H2,1-2H3,(H,29,32)(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPA				Bioorg Med Chem Lett 16: 5066-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.040 BindingDB Entry DOI: 10.7270/Q2FJ2GD3
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50192515 (CHEMBL384247 | phenyl 2-(3,4-dimethylphenoxy)-5-((...) Show SMILES Cc1ccc(Oc2ccc(cc2NC(=O)Oc2ccccc2)C(=O)NCCN2CCCC2)cc1C Show InChI InChI=1S/C28H31N3O4/c1-20-10-12-24(18-21(20)2)34-26-13-11-22(27(32)29-14-17-31-15-6-7-16-31)19-25(26)30-28(33)35-23-8-4-3-5-9-23/h3-5,8-13,18-19H,6-7,14-17H2,1-2H3,(H,29,32)(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPA				Bioorg Med Chem Lett 16: 5066-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.040 BindingDB Entry DOI: 10.7270/Q2FJ2GD3
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50192515 (CHEMBL384247 | phenyl 2-(3,4-dimethylphenoxy)-5-((...) Show SMILES Cc1ccc(Oc2ccc(cc2NC(=O)Oc2ccccc2)C(=O)NCCN2CCCC2)cc1C Show InChI InChI=1S/C28H31N3O4/c1-20-10-12-24(18-21(20)2)34-26-13-11-22(27(32)29-14-17-31-15-6-7-16-31)19-25(26)30-28(33)35-23-8-4-3-5-9-23/h3-5,8-13,18-19H,6-7,14-17H2,1-2H3,(H,29,32)(H,30,33)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPA				Bioorg Med Chem Lett 16: 5066-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.040 BindingDB Entry DOI: 10.7270/Q2FJ2GD3
					More data for this Ligand-Target Pair