BDBM50192517 4-(3,4-dimethylphenoxy)-3-propionamido-N-(2-(pyrrolidin-1-yl)ethyl)benzamide::CHEMBL214177

SMILES: CCC(=O)Nc1cc(ccc1Oc1ccc(C)c(C)c1)C(=O)NCCN1CCCC1

InChI Key: InChIKey=GBYGZYDTFFMMED-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50192517 (4-(3,4-dimethylphenoxy)-3-propionamido-N-(2-(pyrro...) Show SMILES CCC(=O)Nc1cc(ccc1Oc1ccc(C)c(C)c1)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C24H31N3O3/c1-4-23(28)26-21-16-19(24(29)25-11-14-27-12-5-6-13-27)8-10-22(21)30-20-9-7-17(2)18(3)15-20/h7-10,15-16H,4-6,11-14H2,1-3H3,(H,25,29)(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPA				Bioorg Med Chem Lett 16: 5066-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.040 BindingDB Entry DOI: 10.7270/Q2FJ2GD3
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50192517 (4-(3,4-dimethylphenoxy)-3-propionamido-N-(2-(pyrro...) Show SMILES CCC(=O)Nc1cc(ccc1Oc1ccc(C)c(C)c1)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C24H31N3O3/c1-4-23(28)26-21-16-19(24(29)25-11-14-27-12-5-6-13-27)8-10-22(21)30-20-9-7-17(2)18(3)15-20/h7-10,15-16H,4-6,11-14H2,1-3H3,(H,25,29)(H,26,28)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPA				Bioorg Med Chem Lett 16: 5066-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.040 BindingDB Entry DOI: 10.7270/Q2FJ2GD3
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50192517 (4-(3,4-dimethylphenoxy)-3-propionamido-N-(2-(pyrro...) Show SMILES CCC(=O)Nc1cc(ccc1Oc1ccc(C)c(C)c1)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C24H31N3O3/c1-4-23(28)26-21-16-19(24(29)25-11-14-27-12-5-6-13-27)8-10-22(21)30-20-9-7-17(2)18(3)15-20/h7-10,15-16H,4-6,11-14H2,1-3H3,(H,25,29)(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPA				Bioorg Med Chem Lett 16: 5066-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.040 BindingDB Entry DOI: 10.7270/Q2FJ2GD3
					More data for this Ligand-Target Pair