BDBM50192576 (R)-4-(5-oxo-3-phenyl-4,5-dihydro-1,2,4-triazol-1-yl)-N-(2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)piperidine-1-carboxamide::CHEMBL384799

SMILES: FC(F)(F)CN1c2ccccc2C(=N[C@@H](NC(=O)N2CCC(CC2)n2nc([nH]c2=O)-c2ccccc2)C1=O)c1ccccc1

InChI Key: InChIKey=SAPYIDWHUPVUPO-MHZLTWQESA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50192576 ((R)-4-(5-oxo-3-phenyl-4,5-dihydro-1,2,4-triazol-1-...) Show SMILES FC(F)(F)CN1c2ccccc2C(=N[C@@H](NC(=O)N2CCC(CC2)n2nc([nH]c2=O)-c2ccccc2)C1=O)c1ccccc1 |c:13| Show InChI InChI=1S/C31H28F3N7O3/c32-31(33,34)19-40-24-14-8-7-13-23(24)25(20-9-3-1-4-10-20)35-27(28(40)42)37-29(43)39-17-15-22(16-18-39)41-30(44)36-26(38-41)21-11-5-2-6-12-21/h1-14,22,27H,15-19H2,(H,37,43)(H,36,38,44)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from human recombinant CGRP receptor				Bioorg Med Chem Lett 16: 5052-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.044 BindingDB Entry DOI: 10.7270/Q29S1QNX
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50192576 ((R)-4-(5-oxo-3-phenyl-4,5-dihydro-1,2,4-triazol-1-...) Show SMILES FC(F)(F)CN1c2ccccc2C(=N[C@@H](NC(=O)N2CCC(CC2)n2nc([nH]c2=O)-c2ccccc2)C1=O)c1ccccc1 |c:13| Show InChI InChI=1S/C31H28F3N7O3/c32-31(33,34)19-40-24-14-8-7-13-23(24)25(20-9-3-1-4-10-20)35-27(28(40)42)37-29(43)39-17-15-22(16-18-39)41-30(44)36-26(38-41)21-11-5-2-6-12-21/h1-14,22,27H,15-19H2,(H,37,43)(H,36,38,44)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production				Bioorg Med Chem Lett 16: 5052-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.044 BindingDB Entry DOI: 10.7270/Q29S1QNX
					More data for this Ligand-Target Pair