BDBM50192717 7-amino-19-methyl-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one::CHEMBL373397

SMILES: CCCn1c2ccc(N)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12

InChI Key: InChIKey=LHRVQMLHEAXHIL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50192717 (7-amino-19-methyl-3-propyl-3,13,19,20-tetraazahexa...) Show SMILES CCCn1c2ccc(N)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C23H23N5O/c1-3-8-28-18-7-4-12(24)9-14(18)20-15-10-25-23(29)21(15)19-13(22(20)28)5-6-17-16(19)11-27(2)26-17/h4,7,9,11H,3,5-6,8,10,24H2,1-2H3,(H,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 16: 5368-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.066 BindingDB Entry DOI: 10.7270/Q2SQ901V
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50192717 (7-amino-19-methyl-3-propyl-3,13,19,20-tetraazahexa...) Show SMILES CCCn1c2ccc(N)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C23H23N5O/c1-3-8-28-18-7-4-12(24)9-14(18)20-15-10-25-23(29)21(15)19-13(22(20)28)5-6-17-16(19)11-27(2)26-17/h4,7,9,11H,3,5-6,8,10,24H2,1-2H3,(H,25,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of Tie2				Bioorg Med Chem Lett 16: 5368-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.066 BindingDB Entry DOI: 10.7270/Q2SQ901V
					More data for this Ligand-Target Pair