BDBM50192719 3-{3-butyl-19-methyl-14-oxo-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}-1-(4-methoxyphenyl)urea::CHEMBL374736

SMILES: CCCCn1c2ccc(NC(=O)Nc3ccc(OC)cc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12

InChI Key: InChIKey=WLQXMZGRKAHBAE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50192719 (3-{3-butyl-19-methyl-14-oxo-3,13,19,20-tetraazahex...) Show SMILES CCCCn1c2ccc(NC(=O)Nc3ccc(OC)cc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C32H32N6O3/c1-4-5-14-38-26-13-8-19(35-32(40)34-18-6-9-20(41-3)10-7-18)15-22(26)28-23-16-33-31(39)29(23)27-21(30(28)38)11-12-25-24(27)17-37(2)36-25/h6-10,13,15,17H,4-5,11-12,14,16H2,1-3H3,(H,33,39)(H2,34,35,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 16: 5368-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.066 BindingDB Entry DOI: 10.7270/Q2SQ901V
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50192719 (3-{3-butyl-19-methyl-14-oxo-3,13,19,20-tetraazahex...) Show SMILES CCCCn1c2ccc(NC(=O)Nc3ccc(OC)cc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C32H32N6O3/c1-4-5-14-38-26-13-8-19(35-32(40)34-18-6-9-20(41-3)10-7-18)15-22(26)28-23-16-33-31(39)29(23)27-21(30(28)38)11-12-25-24(27)17-37(2)36-25/h6-10,13,15,17H,4-5,11-12,14,16H2,1-3H3,(H,33,39)(H2,34,35,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of Tie2				Bioorg Med Chem Lett 16: 5368-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.066 BindingDB Entry DOI: 10.7270/Q2SQ901V
					More data for this Ligand-Target Pair