BDBM50192734 CHEMBL3947301

SMILES: OCC1(CC(=NN1C(=O)Nc1ccc(F)cc1)c1ccccc1)c1ccc(F)cc1

InChI Key: InChIKey=TWFRJVDERSSRTP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated calcium channel (Homo sapiens (Human))	BDBM50192734 (CHEMBL3947301) Show SMILES OCC1(CC(=NN1C(=O)Nc1ccc(F)cc1)c1ccccc1)c1ccc(F)cc1 |c:4| Show InChI InChI=1S/C23H19F2N3O2/c24-18-8-6-17(7-9-18)23(15-29)14-21(16-4-2-1-3-5-16)27-28(23)22(30)26-20-12-10-19(25)11-13-20/h1-13,29H,14-15H2,(H,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Inhibition of recombinant T-type calcium channel Cav1.2 (unknown origin) expressed in HEK293 cells assessed as inhibition of Kcl-induced calcium infl...				J Med Chem 59: 8398-411 (2016) BindingDB Entry DOI: 10.7270/Q2J67JWK
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50192734 (CHEMBL3947301) Show SMILES OCC1(CC(=NN1C(=O)Nc1ccc(F)cc1)c1ccccc1)c1ccc(F)cc1 |c:4| Show InChI InChI=1S/C23H19F2N3O2/c24-18-8-6-17(7-9-18)23(15-29)14-21(16-4-2-1-3-5-16)27-28(23)22(30)26-20-12-10-19(25)11-13-20/h1-13,29H,14-15H2,(H,26,30)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Inhibition of human T-type calcium channel Cav3.2 expressed in CHO cells assessed as inhibition of calcium tail current at -90 mV holding potential m...				J Med Chem 59: 8398-411 (2016) BindingDB Entry DOI: 10.7270/Q2J67JWK
					More data for this Ligand-Target Pair