BDBM50192847 CHEMBL3358970

SMILES: COc1cc(OC)c(c(OC)c1)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12

InChI Key: InChIKey=PEGLRWPDCZBRDM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50192847 (CHEMBL3358970) Show SMILES COc1cc(OC)c(c(OC)c1)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12 |(3.15,-16.43,;4.49,-17.21,;5.83,-16.43,;5.83,-14.88,;7.16,-14.12,;7.16,-12.58,;5.83,-11.82,;8.5,-14.88,;8.5,-16.42,;9.83,-17.18,;9.84,-18.71,;7.17,-17.2,;9.83,-14.11,;11.16,-14.87,;12.49,-14.11,;12.49,-12.57,;11.16,-11.79,;9.83,-12.57,;8.49,-11.8,;13.81,-14.88,;13.97,-16.42,;15.48,-16.75,;16.25,-15.41,;17.75,-15.08,;18.23,-13.63,;17.2,-12.49,;15.7,-12.81,;15.22,-14.26,)| Show InChI InChI=1S/C21H19N3O4/c1-26-12-8-17(27-2)19(18(9-12)28-3)20-21(25)23-11-16(24-20)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate				J Med Chem 58: 170-82 (2015) Article DOI: 10.1021/jm500373x BindingDB Entry DOI: 10.7270/Q2ZG6V0R
					More data for this Ligand-Target Pair