BDBM50192850 CHEMBL3358994

SMILES: COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cccc(Cl)c1

InChI Key: InChIKey=TVHBNAVDYMOCTJ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50192850 (CHEMBL3358994) Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H17ClN2O4/c1-24-15-8-12(9-16(25-2)18(15)26-3)17-19(23)21-10-14(22-17)11-5-4-6-13(20)7-11/h4-10H,1-3H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of human c-KiT				J Med Chem 58: 170-82 (2015) Article DOI: 10.1021/jm500373x BindingDB Entry DOI: 10.7270/Q2ZG6V0R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50192850 (CHEMBL3358994) Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H17ClN2O4/c1-24-15-8-12(9-16(25-2)18(15)26-3)17-19(23)21-10-14(22-17)11-5-4-6-13(20)7-11/h4-10H,1-3H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate				J Med Chem 58: 170-82 (2015) Article DOI: 10.1021/jm500373x BindingDB Entry DOI: 10.7270/Q2ZG6V0R
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50192850 (CHEMBL3358994) Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H17ClN2O4/c1-24-15-8-12(9-16(25-2)18(15)26-3)17-19(23)21-10-14(22-17)11-5-4-6-13(20)7-11/h4-10H,1-3H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 using poly(Glu,Tyr) substrate				J Med Chem 58: 170-82 (2015) Article DOI: 10.1021/jm500373x BindingDB Entry DOI: 10.7270/Q2ZG6V0R
					More data for this Ligand-Target Pair