BDBM50192863 CHEMBL3358979

SMILES: COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cn(C)c2ccccc12

InChI Key: InChIKey=JOGPBZFNAVWJTP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50192863 (CHEMBL3358979) Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C22H21N3O4/c1-25-12-15(14-7-5-6-8-17(14)25)16-11-23-22(26)20(24-16)13-9-18(27-2)21(29-4)19(10-13)28-3/h5-12H,1-4H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate				J Med Chem 58: 170-82 (2015) Article DOI: 10.1021/jm500373x BindingDB Entry DOI: 10.7270/Q2ZG6V0R
					More data for this Ligand-Target Pair