Found 5 hits for monomerid = 50192906 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50192906
(8S-hydroxylobel-9-ene | CHEMBL213613)Show SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 960 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070 BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50192906
(8S-hydroxylobel-9-ene | CHEMBL213613)Show SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070 BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this Ligand-Target Pair | |
Vesicular monoamine transporter 2 (VMAT2)
(Rattus norvegicus (Rat)) | BDBM50192906
(8S-hydroxylobel-9-ene | CHEMBL213613)Show SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m0/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 6.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070 BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor
(Rattus norvegicus (Rat)) | BDBM50192906
(8S-hydroxylobel-9-ene | CHEMBL213613)Show SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description Inhibition of [3H]MLA binding to alpha7 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070 BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit
(Rattus norvegicus (Rat)) | BDBM50192906
(8S-hydroxylobel-9-ene | CHEMBL213613)Show SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description Inhibition of [3H]NIC binding to alpha4beta2 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070 BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this Ligand-Target Pair | |