BDBM50193202 (S)-N-(3-(trifluoromethyl)benzyl)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carboxamide::CHEMBL218930

SMILES: FC(F)(F)c1cccc(CNC(=O)N2CCC[C@H]2CN2CCCC2)c1

InChI Key: InChIKey=AGOURBNJZXFZGH-INIZCTEOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193202   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50193202 ((S)-N-(3-(trifluoromethyl)benzyl)-2-(pyrrolidin-1-...) Show SMILES FC(F)(F)c1cccc(CNC(=O)N2CCC[C@H]2CN2CCCC2)c1 Show InChI InChI=1S/C18H24F3N3O/c19-18(20,21)15-6-3-5-14(11-15)12-22-17(25)24-10-4-7-16(24)13-23-8-1-2-9-23/h3,5-6,11,16H,1-2,4,7-10,12-13H2,(H,22,25)/t16-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assay				Bioorg Med Chem Lett 16: 5303-8 (2006) Article DOI: 10.1016/j.bmcl.2006.07.093 BindingDB Entry DOI: 10.7270/Q2RV0NBD
					More data for this Ligand-Target Pair