null

SMILES: Cc1cccc(c1)C(CCN1CCN(CC1)c1ccccn1)N=O

InChI Key: InChIKey=DDIDCMYJOMXBHB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50193368 ((E)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)pr...) Show SMILES Cc1cccc(c1)C(CCN1CCN(CC1)c1ccccn1)N=O Show InChI InChI=1S/C19H24N4O/c1-16-5-4-6-17(15-16)18(21-24)8-10-22-11-13-23(14-12-22)19-7-2-3-9-20-19/h2-7,9,15,18H,8,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assay				J Med Chem 49: 5093-109 (2006) Article DOI: 10.1021/jm060279f BindingDB Entry DOI: 10.7270/Q2CJ8D4B
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50193368 ((E)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)pr...) Show SMILES Cc1cccc(c1)C(CCN1CCN(CC1)c1ccccn1)N=O Show InChI InChI=1S/C19H24N4O/c1-16-5-4-6-17(15-16)18(21-24)8-10-22-11-13-23(14-12-22)19-7-2-3-9-20-19/h2-7,9,15,18H,8,10-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Activity at human recombinant D4.4 receptor expressed in HEK293 cells by FLIPR assay				J Med Chem 49: 5093-109 (2006) Article DOI: 10.1021/jm060279f BindingDB Entry DOI: 10.7270/Q2CJ8D4B
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50193368 ((E)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)pr...) Show SMILES Cc1cccc(c1)C(CCN1CCN(CC1)c1ccccn1)N=O Show InChI InChI=1S/C19H24N4O/c1-16-5-4-6-17(15-16)18(21-24)8-10-22-11-13-23(14-12-22)19-7-2-3-9-20-19/h2-7,9,15,18H,8,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Agonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assay				J Med Chem 49: 5093-109 (2006) Article DOI: 10.1021/jm060279f BindingDB Entry DOI: 10.7270/Q2CJ8D4B
					More data for this Ligand-Target Pair