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SMILES: C[C@@H](N[C@H]1CCCC[C@@H]1NC(=O)c1ccc(Cl)c(Cl)c1)c1cccc2ccccc12

InChI Key: InChIKey=PMYMENPPVGYIAN-XRJVTAMDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193411   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Rattus norvegicus)		BDBM50193411
PNG
(3,4-dichloro-N-((1S,2S)-2-((R)-1-(naphthalen-1-yl)...)
Show SMILES C[C@@H](N[C@H]1CCCC[C@@H]1NC(=O)c1ccc(Cl)c(Cl)c1)c1cccc2ccccc12
Show InChI InChI=1S/C25H26Cl2N2O/c1-16(19-10-6-8-17-7-2-3-9-20(17)19)28-23-11-4-5-12-24(23)29-25(30)18-13-14-21(26)22(27)15-18/h2-3,6-10,13-16,23-24,28H,4-5,11-12H2,1H3,(H,29,30)/t16-,23+,24+/m1/s1
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PubMed
n/an/a 330n/an/an/an/an/an/a



CNRS

Curated by ChEMBL


Assay Description
Activity at rat CaSR in CHO cells assessed as inhibition of calcium ion-induced [3H]inositol phosphate accumulation

J Med Chem 49: 5119-28 (2006)


Article DOI: 10.1021/jm051233+
BindingDB Entry DOI: 10.7270/Q2DJ5GFC
More data for this
Ligand-Target Pair