null

SMILES: CC(C)Oc1cccc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C

InChI Key: InChIKey=SMILMVOWBJECEY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50193717 (CHEMBL3932025) Show SMILES CC(C)Oc1cccc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C Show InChI InChI=1S/C19H24N2O3/c1-11(2)24-17-8-6-7-15(14(17)5)18(22)20-10-16-12(3)9-13(4)21-19(16)23/h6-9,11H,10H2,1-5H3,(H,20,22)(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...				J Med Chem 59: 8306-25 (2016) Article DOI: 10.1021/acs.jmedchem.6b00515 BindingDB Entry DOI: 10.7270/Q2J1053B
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50193717 (CHEMBL3932025) Show SMILES CC(C)Oc1cccc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C Show InChI InChI=1S/C19H24N2O3/c1-11(2)24-17-8-6-7-15(14(17)5)18(22)20-10-16-12(3)9-13(4)21-19(16)23/h6-9,11H,10H2,1-5H3,(H,20,22)(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	252	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex by ITC analysis				J Med Chem 59: 8306-25 (2016) Article DOI: 10.1021/acs.jmedchem.6b00515 BindingDB Entry DOI: 10.7270/Q2J1053B
					More data for this Ligand-Target Pair