BDBM50193802 (S)-6-(4-(2-(3-(3-ethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)-2-hydroxypropylamino)-2-methylpropyl)phenoxy)nicotinamide::CHEMBL384560

SMILES: CCn1c2c(OC[C@@H](O)CNC(C)(C)Cc3ccc(Oc4ccc(cn4)C(N)=O)cc3)cccc2[nH]c1=O

InChI Key: InChIKey=XUDGCOWUVGYAJW-FQEVSTJZSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50193802 ((S)-6-(4-(2-(3-(3-ethyl-2-oxo-2,3-dihydro-1H-benzo...) Show SMILES CCn1c2c(OC[C@@H](O)CNC(C)(C)Cc3ccc(Oc4ccc(cn4)C(N)=O)cc3)cccc2[nH]c1=O Show InChI InChI=1S/C28H33N5O5/c1-4-33-25-22(32-27(33)36)6-5-7-23(25)37-17-20(34)16-31-28(2,3)14-18-8-11-21(12-9-18)38-24-13-10-19(15-30-24)26(29)35/h5-13,15,20,31,34H,4,14,16-17H2,1-3H3,(H2,29,35)(H,32,36)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta-2 adrenergic receptor expressed in CHO cells assessed as cAMP levels				Bioorg Med Chem Lett 16: 5691-4 (2006) Article DOI: 10.1016/j.bmcl.2006.08.010 BindingDB Entry DOI: 10.7270/Q2251HVR
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50193802 ((S)-6-(4-(2-(3-(3-ethyl-2-oxo-2,3-dihydro-1H-benzo...) Show SMILES CCn1c2c(OC[C@@H](O)CNC(C)(C)Cc3ccc(Oc4ccc(cn4)C(N)=O)cc3)cccc2[nH]c1=O Show InChI InChI=1S/C28H33N5O5/c1-4-33-25-22(32-27(33)36)6-5-7-23(25)37-17-20(34)16-31-28(2,3)14-18-8-11-21(12-9-18)38-24-13-10-19(15-30-24)26(29)35/h5-13,15,20,31,34H,4,14,16-17H2,1-3H3,(H2,29,35)(H,32,36)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as cAMP levels				Bioorg Med Chem Lett 16: 5691-4 (2006) Article DOI: 10.1016/j.bmcl.2006.08.010 BindingDB Entry DOI: 10.7270/Q2251HVR
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50193802 ((S)-6-(4-(2-(3-(3-ethyl-2-oxo-2,3-dihydro-1H-benzo...) Show SMILES CCn1c2c(OC[C@@H](O)CNC(C)(C)Cc3ccc(Oc4ccc(cn4)C(N)=O)cc3)cccc2[nH]c1=O Show InChI InChI=1S/C28H33N5O5/c1-4-33-25-22(32-27(33)36)6-5-7-23(25)37-17-20(34)16-31-28(2,3)14-18-8-11-21(12-9-18)38-24-13-10-19(15-30-24)26(29)35/h5-13,15,20,31,34H,4,14,16-17H2,1-3H3,(H2,29,35)(H,32,36)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP levels				Bioorg Med Chem Lett 16: 5691-4 (2006) Article DOI: 10.1016/j.bmcl.2006.08.010 BindingDB Entry DOI: 10.7270/Q2251HVR
					More data for this Ligand-Target Pair