BDBM50193860 4-{3-(5-chloro-pyridin-2-ylcarbamoyl)-4-[4-(N,N-dimethyl-carbamimidoyl)-benzoylamino]-phenylsulfanyl}-benzoic acid::CHEMBL218528

SMILES: CN(C)C(=N)c1ccc(cc1)C(=O)Nc1ccc(Sc2ccc(cc2)C(O)=O)cc1C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=CUSCSOGEMCLGCL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50193860 (4-{3-(5-chloro-pyridin-2-ylcarbamoyl)-4-[4-(N,N-di...) Show SMILES CN(C)C(=N)c1ccc(cc1)C(=O)Nc1ccc(Sc2ccc(cc2)C(O)=O)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C29H24ClN5O4S/c1-35(2)26(31)17-3-5-18(6-4-17)27(36)33-24-13-12-22(40-21-10-7-19(8-11-21)29(38)39)15-23(24)28(37)34-25-14-9-20(30)16-32-25/h3-16,31H,1-2H3,(H,33,36)(H,38,39)(H,32,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Portola Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cells				Bioorg Med Chem Lett 16: 5507-12 (2006) Article DOI: 10.1016/j.bmcl.2006.08.039 BindingDB Entry DOI: 10.7270/Q2SF2X05
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