BDBM50193888 CHEMBL218842::N-(4-butylphenyl)-7-(2,6-dimethylphenyl)-5-methylbenzo[e][1,2,4]triazin-3-amine::US8481536, 341

SMILES: CCCCc1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)cc1

InChI Key: InChIKey=KJIBUWZGIDVJIY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193888 (CHEMBL218842 | N-(4-butylphenyl)-7-(2,6-dimethylph...) Show SMILES CCCCc1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)cc1 Show InChI InChI=1S/C26H28N4/c1-5-6-10-20-11-13-22(14-12-20)27-26-28-25-19(4)15-21(16-23(25)29-30-26)24-17(2)8-7-9-18(24)3/h7-9,11-16H,5-6,10H2,1-4H3,(H,27,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Src kinase				Bioorg Med Chem Lett 16: 5546-50 (2006) Article DOI: 10.1016/j.bmcl.2006.08.035 BindingDB Entry DOI: 10.7270/Q2SN08MP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193888 (CHEMBL218842 | N-(4-butylphenyl)-7-(2,6-dimethylph...) Show SMILES CCCCc1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)cc1 Show InChI InChI=1S/C26H28N4/c1-5-6-10-20-11-13-22(14-12-20)27-26-28-25-19(4)15-21(16-23(25)29-30-26)24-17(2)8-7-9-18(24)3/h7-9,11-16H,5-6,10H2,1-4H3,(H,27,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair