BDBM50193893 7-mesityl-5-methyl-N-phenylbenzo[e][1,2,4]triazin-3-amine::CHEMBL218109::US8481536, 317

SMILES: Cc1cc(C)c(c(C)c1)-c1cc(C)c2nc(Nc3ccccc3)nnc2c1

InChI Key: InChIKey=ZHVJPJYSKUEODB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193893   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193893 (7-mesityl-5-methyl-N-phenylbenzo[e][1,2,4]triazin-...) Show SMILES Cc1cc(C)c(c(C)c1)-c1cc(C)c2nc(Nc3ccccc3)nnc2c1 Show InChI InChI=1S/C23H22N4/c1-14-10-15(2)21(16(3)11-14)18-12-17(4)22-20(13-18)26-27-23(25-22)24-19-8-6-5-7-9-19/h5-13H,1-4H3,(H,24,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Src kinase				Bioorg Med Chem Lett 16: 5546-50 (2006) Article DOI: 10.1016/j.bmcl.2006.08.035 BindingDB Entry DOI: 10.7270/Q2SN08MP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193893 (7-mesityl-5-methyl-N-phenylbenzo[e][1,2,4]triazin-...) Show SMILES Cc1cc(C)c(c(C)c1)-c1cc(C)c2nc(Nc3ccccc3)nnc2c1 Show InChI InChI=1S/C23H22N4/c1-14-10-15(2)21(16(3)11-14)18-12-17(4)22-20(13-18)26-27-23(25-22)24-19-8-6-5-7-9-19/h5-13H,1-4H3,(H,24,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair