BDBM50193907 7-(2,6-dimethylphenyl)-5-methyl-N-(pyridin-4-yl)benzo[e][1,2,4]triazin-3-amine::CHEMBL221582::US8481536, 359

SMILES: Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccncc3)nnc2c1

InChI Key: InChIKey=ZJQVYURHZFRKLA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193907   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193907 (7-(2,6-dimethylphenyl)-5-methyl-N-(pyridin-4-yl)be...) Show SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccncc3)nnc2c1 Show InChI InChI=1S/C21H19N5/c1-13-5-4-6-14(2)19(13)16-11-15(3)20-18(12-16)25-26-21(24-20)23-17-7-9-22-10-8-17/h4-12H,1-3H3,(H,22,23,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Src kinase				Bioorg Med Chem Lett 16: 5546-50 (2006) Article DOI: 10.1016/j.bmcl.2006.08.035 BindingDB Entry DOI: 10.7270/Q2SN08MP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193907 (7-(2,6-dimethylphenyl)-5-methyl-N-(pyridin-4-yl)be...) Show SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccncc3)nnc2c1 Show InChI InChI=1S/C21H19N5/c1-13-5-4-6-14(2)19(13)16-11-15(3)20-18(12-16)25-26-21(24-20)23-17-7-9-22-10-8-17/h4-12H,1-3H3,(H,22,23,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair