Found 3 hits for monomerid = 50193910 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50193910
(CHEMBL218102 | N-(3-(2-(diethylamino)ethoxy)phenyl...)Show SMILES CCN(CC)CCOc1cccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)c1 Show InChI InChI=1S/C28H33N5O/c1-6-33(7-2)14-15-34-24-13-9-12-23(18-24)29-28-30-27-21(5)16-22(17-25(27)31-32-28)26-19(3)10-8-11-20(26)4/h8-13,16-18H,6-7,14-15H2,1-5H3,(H,29,30,32) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| US Patent
| n/a | n/a | 10.2 | n/a | n/a | n/a | n/a | n/a | 25 |
TargeGen, Inc.
US Patent
| Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp. |
US Patent US8481536 (2013)
BindingDB Entry DOI: 10.7270/Q2GB22PZ |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50193910
(CHEMBL218102 | N-(3-(2-(diethylamino)ethoxy)phenyl...)Show SMILES CCN(CC)CCOc1cccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)c1 Show InChI InChI=1S/C28H33N5O/c1-6-33(7-2)14-15-34-24-13-9-12-23(18-24)29-28-30-27-21(5)16-22(17-25(27)31-32-28)26-19(3)10-8-11-20(26)4/h8-13,16-18H,6-7,14-15H2,1-5H3,(H,29,30,32) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TargeGen, Inc.
Curated by ChEMBL
| Assay Description Inhibition of Src |
Bioorg Med Chem Lett 17: 602-8 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.006 BindingDB Entry DOI: 10.7270/Q29024MW |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50193910
(CHEMBL218102 | N-(3-(2-(diethylamino)ethoxy)phenyl...)Show SMILES CCN(CC)CCOc1cccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)c1 Show InChI InChI=1S/C28H33N5O/c1-6-33(7-2)14-15-34-24-13-9-12-23(18-24)29-28-30-27-21(5)16-22(17-25(27)31-32-28)26-19(3)10-8-11-20(26)4/h8-13,16-18H,6-7,14-15H2,1-5H3,(H,29,30,32) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TargeGen, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Src kinase |
Bioorg Med Chem Lett 16: 5546-50 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.035 BindingDB Entry DOI: 10.7270/Q2SN08MP |
More data for this Ligand-Target Pair | |