BDBM50194271 (+/-)-3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-cis-6,11-dimethyl-N-(2-phenylethyl)-2,6-methano-3-benzazocine-8-carboxamide::CHEMBL209550

SMILES: C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)NCCc1ccccc1

InChI Key: InChIKey=YDAZIHWOJIXKKE-KGGNFQJGSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194271   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50194271 ((+/-)-3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-...) Show SMILES C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)NCCc1ccccc1 |TLB:8:9:1:14.12.13,15:14:1:4.9.3| Show InChI InChI=1S/C27H34N2O/c1-19-25-17-22-10-11-23(26(30)28-14-12-20-6-4-3-5-7-20)16-24(22)27(19,2)13-15-29(25)18-21-8-9-21/h3-7,10-11,16,19,21,25H,8-9,12-15,17-18H2,1-2H3,(H,28,30)/t19-,25?,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rensselaer Polytechnic Institute Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from human kappa opioid receptor expressed in CHO cells				J Med Chem 49: 5635-9 (2006) Article DOI: 10.1021/jm060278n BindingDB Entry DOI: 10.7270/Q208663G
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50194271 ((+/-)-3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-...) Show SMILES C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)NCCc1ccccc1 |TLB:8:9:1:14.12.13,15:14:1:4.9.3| Show InChI InChI=1S/C27H34N2O/c1-19-25-17-22-10-11-23(26(30)28-14-12-20-6-4-3-5-7-20)16-24(22)27(19,2)13-15-29(25)18-21-8-9-21/h3-7,10-11,16,19,21,25H,8-9,12-15,17-18H2,1-2H3,(H,28,30)/t19-,25?,27-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rensselaer Polytechnic Institute Curated by ChEMBL					Assay Description Antagonist activity against human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding				J Med Chem 49: 5635-9 (2006) Article DOI: 10.1021/jm060278n BindingDB Entry DOI: 10.7270/Q208663G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50194271 ((+/-)-3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-...) Show SMILES C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)NCCc1ccccc1 |TLB:8:9:1:14.12.13,15:14:1:4.9.3| Show InChI InChI=1S/C27H34N2O/c1-19-25-17-22-10-11-23(26(30)28-14-12-20-6-4-3-5-7-20)16-24(22)27(19,2)13-15-29(25)18-21-8-9-21/h3-7,10-11,16,19,21,25H,8-9,12-15,17-18H2,1-2H3,(H,28,30)/t19-,25?,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rensselaer Polytechnic Institute Curated by ChEMBL					Assay Description Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells				J Med Chem 49: 5635-9 (2006) Article DOI: 10.1021/jm060278n BindingDB Entry DOI: 10.7270/Q208663G
					More data for this Ligand-Target Pair