BDBM50194283 CHEMBL221751::N-(2-fluorobenzyl)-4-(4-(5-(2-ethoxyethyl)-2,4,6-trioxo-hexahydropyrimidin-5-yloxy)phenoxy)benzamide

SMILES: CCOCCC1(Oc2ccc(Oc3ccc(cc3)C(=O)NCc3ccccc3F)cc2)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=FWIRQPTYAFFUNS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50194283   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50194283 (CHEMBL221751 | N-(2-fluorobenzyl)-4-(4-(5-(2-ethox...) Show SMILES CCOCCC1(Oc2ccc(Oc3ccc(cc3)C(=O)NCc3ccccc3F)cc2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C28H26FN3O7/c1-2-37-16-15-28(25(34)31-27(36)32-26(28)35)39-22-13-11-21(12-14-22)38-20-9-7-18(8-10-20)24(33)30-17-19-5-3-4-6-23(19)29/h3-14H,2,15-17H2,1H3,(H,30,33)(H2,31,32,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem Lett 16: 5822-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.066 BindingDB Entry DOI: 10.7270/Q27P8Z1R
					More data for this Ligand-Target Pair