BDBM50194300 5-(2-ethoxyethyl)-5-(4-(4-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)phenoxy)phenoxy)pyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL221449

SMILES: CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3nc(no3)-c3ccc(F)cc3)cc2)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=SUMNMUSMCVCNRE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50194300   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50194300 (5-(2-ethoxyethyl)-5-(4-(4-(3-(4-fluorophenyl)-1,2,...) Show SMILES CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3nc(no3)-c3ccc(F)cc3)cc2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C28H23FN4O7/c1-2-37-16-15-28(25(34)31-27(36)32-26(28)35)39-22-13-11-21(12-14-22)38-20-9-5-18(6-10-20)24-30-23(33-40-24)17-3-7-19(29)8-4-17/h3-14H,2,15-16H2,1H3,(H2,31,32,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem Lett 16: 5822-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.066 BindingDB Entry DOI: 10.7270/Q27P8Z1R
					More data for this Ligand-Target Pair