BDBM50194317 (E)-N-(4-chlorophenyl)-2-(2,3-dimethyl-6,7-dihydro-1H-indol-4(5H)-ylidene)hydrazinecarboxamide::CHEMBL217800

SMILES: Cc1[nH]c2CCCC(=NNC(=O)Nc3ccc(Cl)cc3)c2c1C

InChI Key: InChIKey=CWWKNCKBBPUXKA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50194317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50194317 ((E)-N-(4-chlorophenyl)-2-(2,3-dimethyl-6,7-dihydro...) Show SMILES Cc1[nH]c2CCCC(=NNC(=O)Nc3ccc(Cl)cc3)c2c1C |w:8.8| Show InChI InChI=1S/C17H19ClN4O/c1-10-11(2)19-14-4-3-5-15(16(10)14)21-22-17(23)20-13-8-6-12(18)7-9-13/h6-9,19H,3-5H2,1-2H3,(H2,20,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assay				Bioorg Med Chem Lett 16: 5859-63 (2006) Article DOI: 10.1016/j.bmcl.2006.08.057 BindingDB Entry DOI: 10.7270/Q23X868Z
					More data for this Ligand-Target Pair