BDBM50194621 6S-(1'R,2'R-1',5'-dimethyl-1',2'-oxiranyl-4'-hexenyl)-5S-methoxy-4-oxobicyclo[3.1.0]hexane-1R-carbaldehyde::CHEMBL215931::Fumarranol Analog, 7

SMILES: [#6]-[#8][C@@]12[#6]([C@@]3([#6])[#8]-[#6@@H]3-[#6]\[#6]=[#6](\[#6])-[#6])[C@@]1([#6]-[#6]-[#6]2=O)[#6]=O

InChI Key: InChIKey=ILOPCBGGQTWPKD-LMINUHAASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50194621 (6S-(1'R,2'R-1',5'-dimethyl-1',2'-oxiranyl-4'-hexen...) Show SMILES [#6]-[#8][C@@]12[#6]([C@@]3([#6])[#8]-[#6@@H]3-[#6]\[#6]=[#6](\[#6])-[#6])[C@@]1([#6]-[#6]-[#6]2=O)[#6]=O Show InChI InChI=1S/C16H22O4/c1-10(2)5-6-12-14(3,20-12)13-15(9-17)8-7-11(18)16(13,15)19-4/h5,9,12-13H,6-8H2,1-4H3/t12-,13?,14+,15-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human MetAP2				J Med Chem 49: 5645-8 (2006) Article DOI: 10.1021/jm060559v BindingDB Entry DOI: 10.7270/Q2PN959W
					More data for this Ligand-Target Pair
Methionine aminopeptidase (MetAP2) (Plasmodium falciparum)	BDBM50194621 (6S-(1'R,2'R-1',5'-dimethyl-1',2'-oxiranyl-4'-hexen...) Show SMILES [#6]-[#8][C@@]12[#6]([C@@]3([#6])[#8]-[#6@@H]3-[#6]\[#6]=[#6](\[#6])-[#6])[C@@]1([#6]-[#6]-[#6]2=O)[#6]=O Show InChI InChI=1S/C16H22O4/c1-10(2)5-6-12-14(3,20-12)13-15(9-17)8-7-11(18)16(13,15)19-4/h5,9,12-13H,6-8H2,1-4H3/t12-,13?,14+,15-,16+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins School of Medicine					Assay Description Enzyme affinity assay using Fumarranol analogs with plasmodium falciparum methionine aminopeptidases (PfMetAPs).				Chem Biol 16: 193-202 (2009) Article DOI: 10.1016/j.chembiol.2009.01.006 BindingDB Entry DOI: 10.7270/Q2WS8RQ5
					More data for this Ligand-Target Pair