BDBM50194693 6-o-tolylquinazolin-2-amine::CHEMBL215952

SMILES: Cc1ccccc1-c1ccc2nc(N)ncc2c1

InChI Key: InChIKey=RAWAQXBVMDKSIO-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50194693 (6-o-tolylquinazolin-2-amine | CHEMBL215952) Show SMILES Cc1ccccc1-c1ccc2nc(N)ncc2c1 Show InChI InChI=1S/C15H13N3/c1-10-4-2-3-5-13(10)11-6-7-14-12(8-11)9-17-15(16)18-14/h2-9H,1H3,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of p38-alpha by HTRF kinase assay				J Med Chem 49: 5671-86 (2006) Article DOI: 10.1021/jm0605482 BindingDB Entry DOI: 10.7270/Q29G5MFD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50194693 (6-o-tolylquinazolin-2-amine | CHEMBL215952) Show SMILES Cc1ccccc1-c1ccc2nc(N)ncc2c1 Show InChI InChI=1S/C15H13N3/c1-10-4-2-3-5-13(10)11-6-7-14-12(8-11)9-17-15(16)18-14/h2-9H,1H3,(H2,16,17,18)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of Lck by HTRF kinase assay				J Med Chem 49: 5671-86 (2006) Article DOI: 10.1021/jm0605482 BindingDB Entry DOI: 10.7270/Q29G5MFD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50194693 (6-o-tolylquinazolin-2-amine | CHEMBL215952) Show SMILES Cc1ccccc1-c1ccc2nc(N)ncc2c1 Show InChI InChI=1S/C15H13N3/c1-10-4-2-3-5-13(10)11-6-7-14-12(8-11)9-17-15(16)18-14/h2-9H,1H3,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of KDR by HTRF kinase assay				J Med Chem 49: 5671-86 (2006) Article DOI: 10.1021/jm0605482 BindingDB Entry DOI: 10.7270/Q29G5MFD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50194693 (6-o-tolylquinazolin-2-amine | CHEMBL215952) Show SMILES Cc1ccccc1-c1ccc2nc(N)ncc2c1 Show InChI InChI=1S/C15H13N3/c1-10-4-2-3-5-13(10)11-6-7-14-12(8-11)9-17-15(16)18-14/h2-9H,1H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	9.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of Jak3 by HTRF kinase assay				J Med Chem 49: 5671-86 (2006) Article DOI: 10.1021/jm0605482 BindingDB Entry DOI: 10.7270/Q29G5MFD
					More data for this Ligand-Target Pair