BDBM50195081 2-((5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyridin-2-yl)methyl)-tetrahydro-2H-pyran-2-carboxylic acid::CHEMBL435512

SMILES: Cc1oc(nc1CCOc1ccc(CC2(CCCCO2)C(O)=O)nc1)-c1ccccc1

InChI Key: InChIKey=NODVIYUFBGWXDK-UHFFFAOYSA-N

Data: 2 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50195081   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50195081 (2-((5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyri...) Show SMILES Cc1oc(nc1CCOc1ccc(CC2(CCCCO2)C(O)=O)nc1)-c1ccccc1 Show InChI InChI=1S/C24H26N2O5/c1-17-21(26-22(31-17)18-7-3-2-4-8-18)11-14-29-20-10-9-19(25-16-20)15-24(23(27)28)12-5-6-13-30-24/h2-4,7-10,16H,5-6,11-15H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global R&D Curated by ChEMBL					Assay Description Displacement of radiolabeled darglitazone from human PPAR gamma by SPA assay				Bioorg Med Chem Lett 16: 6116-9 (2006) Article DOI: 10.1016/j.bmcl.2006.08.105 BindingDB Entry DOI: 10.7270/Q2H131P4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50195081 (2-((5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyri...) Show SMILES Cc1oc(nc1CCOc1ccc(CC2(CCCCO2)C(O)=O)nc1)-c1ccccc1 Show InChI InChI=1S/C24H26N2O5/c1-17-21(26-22(31-17)18-7-3-2-4-8-18)11-14-29-20-10-9-19(25-16-20)15-24(23(27)28)12-5-6-13-30-24/h2-4,7-10,16H,5-6,11-15H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global R&D Curated by ChEMBL					Assay Description Displacement of radiolabeled GW2331 from human PPAR alpha by SPA assay				Bioorg Med Chem Lett 16: 6116-9 (2006) Article DOI: 10.1016/j.bmcl.2006.08.105 BindingDB Entry DOI: 10.7270/Q2H131P4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50195081 (2-((5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyri...) Show SMILES Cc1oc(nc1CCOc1ccc(CC2(CCCCO2)C(O)=O)nc1)-c1ccccc1 Show InChI InChI=1S/C24H26N2O5/c1-17-21(26-22(31-17)18-7-3-2-4-8-18)11-14-29-20-10-9-19(25-16-20)15-24(23(27)28)12-5-6-13-30-24/h2-4,7-10,16H,5-6,11-15H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global R&D Curated by ChEMBL					Assay Description Agonist activity at human PPAR alpha in HepG2 cells by PPAR-GAL4 transactivation assay				Bioorg Med Chem Lett 16: 6116-9 (2006) Article DOI: 10.1016/j.bmcl.2006.08.105 BindingDB Entry DOI: 10.7270/Q2H131P4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50195081 (2-((5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyri...) Show SMILES Cc1oc(nc1CCOc1ccc(CC2(CCCCO2)C(O)=O)nc1)-c1ccccc1 Show InChI InChI=1S/C24H26N2O5/c1-17-21(26-22(31-17)18-7-3-2-4-8-18)11-14-29-20-10-9-19(25-16-20)15-24(23(27)28)12-5-6-13-30-24/h2-4,7-10,16H,5-6,11-15H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global R&D Curated by ChEMBL					Assay Description Agonist activity at human PPAR gamma in HepG2 cells by PPAR-GAL4 transactivation assay				Bioorg Med Chem Lett 16: 6116-9 (2006) Article DOI: 10.1016/j.bmcl.2006.08.105 BindingDB Entry DOI: 10.7270/Q2H131P4
					More data for this Ligand-Target Pair