Found 4 hits for monomerid = 50195085 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor
(Homo sapiens (Human)) | BDBM50195085
(2-((2-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyri...)Show SMILES Cc1oc(nc1CCOc1ncc(CC2(CCCO2)C(O)=O)cn1)-c1ccccc1 Show InChI InChI=1S/C22H23N3O5/c1-15-18(25-19(30-15)17-6-3-2-4-7-17)8-11-28-21-23-13-16(14-24-21)12-22(20(26)27)9-5-10-29-22/h2-4,6-7,13-14H,5,8-12H2,1H3,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global R&D
Curated by ChEMBL
| Assay Description Displacement of radiolabeled darglitazone from human PPAR gamma by SPA assay |
Bioorg Med Chem Lett 16: 6116-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.105 BindingDB Entry DOI: 10.7270/Q2H131P4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha (PPAR alpha)
(Homo sapiens (Human)) | BDBM50195085
(2-((2-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyri...)Show SMILES Cc1oc(nc1CCOc1ncc(CC2(CCCO2)C(O)=O)cn1)-c1ccccc1 Show InChI InChI=1S/C22H23N3O5/c1-15-18(25-19(30-15)17-6-3-2-4-7-17)8-11-28-21-23-13-16(14-24-21)12-22(20(26)27)9-5-10-29-22/h2-4,6-7,13-14H,5,8-12H2,1H3,(H,26,27) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global R&D
Curated by ChEMBL
| Assay Description Displacement of radiolabeled GW2331 from human PPAR alpha by SPA assay |
Bioorg Med Chem Lett 16: 6116-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.105 BindingDB Entry DOI: 10.7270/Q2H131P4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor
(Homo sapiens (Human)) | BDBM50195085
(2-((2-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyri...)Show SMILES Cc1oc(nc1CCOc1ncc(CC2(CCCO2)C(O)=O)cn1)-c1ccccc1 Show InChI InChI=1S/C22H23N3O5/c1-15-18(25-19(30-15)17-6-3-2-4-7-17)8-11-28-21-23-13-16(14-24-21)12-22(20(26)27)9-5-10-29-22/h2-4,6-7,13-14H,5,8-12H2,1H3,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
Pfizer Global R&D
Curated by ChEMBL
| Assay Description Agonist activity at human PPAR gamma in HepG2 cells by PPAR-GAL4 transactivation assay |
Bioorg Med Chem Lett 16: 6116-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.105 BindingDB Entry DOI: 10.7270/Q2H131P4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha (PPAR alpha)
(Homo sapiens (Human)) | BDBM50195085
(2-((2-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyri...)Show SMILES Cc1oc(nc1CCOc1ncc(CC2(CCCO2)C(O)=O)cn1)-c1ccccc1 Show InChI InChI=1S/C22H23N3O5/c1-15-18(25-19(30-15)17-6-3-2-4-7-17)8-11-28-21-23-13-16(14-24-21)12-22(20(26)27)9-5-10-29-22/h2-4,6-7,13-14H,5,8-12H2,1H3,(H,26,27) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global R&D
Curated by ChEMBL
| Assay Description Agonist activity at human PPAR alpha in HepG2 cells by PPAR-GAL4 transactivation assay |
Bioorg Med Chem Lett 16: 6116-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.105 BindingDB Entry DOI: 10.7270/Q2H131P4 |
More data for this Ligand-Target Pair | |