Found 3 hits for monomerid = 50195179 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glycine transporter 2
(Homo sapiens (Human)) | BDBM50195179
(2,6-difluoro-N-((4-(morpholine-4-carbonyl)-1-(prop...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2c(F)cccc2F)(CC1)C(=O)N1CCOCC1 Show InChI InChI=1S/C21H29F2N3O5S/c1-2-14-32(29,30)26-8-6-21(7-9-26,20(28)25-10-12-31-13-11-25)15-24-19(27)18-16(22)4-3-5-17(18)23/h3-5H,2,6-15H2,1H3,(H,24,27) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co.
Curated by ChEMBL
| Assay Description Inhibition of human GlyT2 |
Bioorg Med Chem Lett 16: 5968-72 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.131 BindingDB Entry DOI: 10.7270/Q2C82B31 |
More data for this Ligand-Target Pair | |
Glycine transporter 1
(Homo sapiens (Human)) | BDBM50195179
(2,6-difluoro-N-((4-(morpholine-4-carbonyl)-1-(prop...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2c(F)cccc2F)(CC1)C(=O)N1CCOCC1 Show InChI InChI=1S/C21H29F2N3O5S/c1-2-14-32(29,30)26-8-6-21(7-9-26,20(28)25-10-12-31-13-11-25)15-24-19(27)18-16(22)4-3-5-17(18)23/h3-5H,2,6-15H2,1H3,(H,24,27) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 131 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co.
Curated by ChEMBL
| Assay Description Inhibition of human GlyT1 |
Bioorg Med Chem Lett 16: 5968-72 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.131 BindingDB Entry DOI: 10.7270/Q2C82B31 |
More data for this Ligand-Target Pair | |
Sodium- and chloride-dependent taurine transporter
(Homo sapiens (Human)) | BDBM50195179
(2,6-difluoro-N-((4-(morpholine-4-carbonyl)-1-(prop...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2c(F)cccc2F)(CC1)C(=O)N1CCOCC1 Show InChI InChI=1S/C21H29F2N3O5S/c1-2-14-32(29,30)26-8-6-21(7-9-26,20(28)25-10-12-31-13-11-25)15-24-19(27)18-16(22)4-3-5-17(18)23/h3-5H,2,6-15H2,1H3,(H,24,27) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co.
Curated by ChEMBL
| Assay Description Inhibition of human TauT |
Bioorg Med Chem Lett 16: 5968-72 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.131 BindingDB Entry DOI: 10.7270/Q2C82B31 |
More data for this Ligand-Target Pair | |