Found 3 hits for monomerid = 50195183 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glycine transporter 2
(Homo sapiens (Human)) | BDBM50195183
(2,4-dichloro-N-((4-(3-(dimethylamino)pyrrolidine-1...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC1)C(=O)N1CCC(C1)N(C)C Show InChI InChI=1S/C23H34Cl2N4O4S/c1-4-13-34(32,33)29-11-8-23(9-12-29,22(31)28-10-7-18(15-28)27(2)3)16-26-21(30)19-6-5-17(24)14-20(19)25/h5-6,14,18H,4,7-13,15-16H2,1-3H3,(H,26,30) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co.
Curated by ChEMBL
| Assay Description Inhibition of human GlyT2 |
Bioorg Med Chem Lett 16: 5968-72 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.131 BindingDB Entry DOI: 10.7270/Q2C82B31 |
More data for this Ligand-Target Pair | |
Glycine transporter 1
(Homo sapiens (Human)) | BDBM50195183
(2,4-dichloro-N-((4-(3-(dimethylamino)pyrrolidine-1...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC1)C(=O)N1CCC(C1)N(C)C Show InChI InChI=1S/C23H34Cl2N4O4S/c1-4-13-34(32,33)29-11-8-23(9-12-29,22(31)28-10-7-18(15-28)27(2)3)16-26-21(30)19-6-5-17(24)14-20(19)25/h5-6,14,18H,4,7-13,15-16H2,1-3H3,(H,26,30) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 544 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co.
Curated by ChEMBL
| Assay Description Inhibition of human GlyT1 |
Bioorg Med Chem Lett 16: 5968-72 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.131 BindingDB Entry DOI: 10.7270/Q2C82B31 |
More data for this Ligand-Target Pair | |
Sodium- and chloride-dependent taurine transporter
(Homo sapiens (Human)) | BDBM50195183
(2,4-dichloro-N-((4-(3-(dimethylamino)pyrrolidine-1...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC1)C(=O)N1CCC(C1)N(C)C Show InChI InChI=1S/C23H34Cl2N4O4S/c1-4-13-34(32,33)29-11-8-23(9-12-29,22(31)28-10-7-18(15-28)27(2)3)16-26-21(30)19-6-5-17(24)14-20(19)25/h5-6,14,18H,4,7-13,15-16H2,1-3H3,(H,26,30) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co.
Curated by ChEMBL
| Assay Description Inhibition of human TauT |
Bioorg Med Chem Lett 16: 5968-72 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.131 BindingDB Entry DOI: 10.7270/Q2C82B31 |
More data for this Ligand-Target Pair | |