BDBM50195259 CHEMBL3898680

SMILES: NC1CCCCC1C(=O)N[C@@H](Cc1ccc(cc1)-c1cccc(c1)C#N)C#N

InChI Key: InChIKey=SXZPZXJTWPGYTE-HWELCPFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195259   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM50195259 (CHEMBL3898680) Show SMILES NC1CCCCC1C(=O)N[C@@H](Cc1ccc(cc1)-c1cccc(c1)C#N)C#N |r| Show InChI InChI=1S/C23H24N4O/c24-14-17-4-3-5-19(12-17)18-10-8-16(9-11-18)13-20(15-25)27-23(28)21-6-1-2-7-22(21)26/h3-5,8-12,20-22H,1-2,6-7,13,26H2,(H,27,28)/t20-,21?,22?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assay				J Med Chem 59: 9457-9472 (2016) Article DOI: 10.1021/acs.jmedchem.6b01127 BindingDB Entry DOI: 10.7270/Q2Z321K4
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