BDBM50195332 3-(6-amino-2-(1H-benzo[d]imidazol-1-yl)pyrimidin-4-ylamino)-4-methylphenol::CHEMBL375363

SMILES: Cc1ccc(O)cc1Nc1cc(N)nc(n1)-n1cnc2ccccc12

InChI Key: InChIKey=KJXSQSSXPPESAI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50195332 (3-(6-amino-2-(1H-benzo[d]imidazol-1-yl)pyrimidin-4...) Show SMILES Cc1ccc(O)cc1Nc1cc(N)nc(n1)-n1cnc2ccccc12 Show InChI InChI=1S/C18H16N6O/c1-11-6-7-12(25)8-14(11)21-17-9-16(19)22-18(23-17)24-10-20-13-4-2-3-5-15(13)24/h2-10,25H,1H3,(H3,19,21,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	294	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant Lck by ProFlour assay				Bioorg Med Chem Lett 16: 5973-7 (2006) Article DOI: 10.1016/j.bmcl.2006.08.132 BindingDB Entry DOI: 10.7270/Q2028R5P
					More data for this Ligand-Target Pair