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SMILES: O=C1c2ccccc2-c2onc3c(cc(NCCN4CCCCC4)c1c23)N1CCN(CC1)c1ccccc1

InChI Key: InChIKey=JHBMKGKKXFPAMN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195460   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone-lysine N-methyltransferase EHMT2


(Homo sapiens (Human))		BDBM50195460
PNG
(CHEMBL3954248)
Show SMILES O=C1c2ccccc2-c2onc3c(cc(NCCN4CCCCC4)c1c23)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C31H33N5O2/c37-30-23-11-5-6-12-24(23)31-28-27(30)25(32-13-16-34-14-7-2-8-15-34)21-26(29(28)33-38-31)36-19-17-35(18-20-36)22-9-3-1-4-10-22/h1,3-6,9-12,21,32H,2,7-8,13-20H2
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.68E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of G9a (unknown origin) using biotinylated-histone H3 (1 to 21 residues)/S-adenosyl-methionine as substrate/methyl donor after 3 hrs by Al...

Bioorg Med Chem 24: 6102-6108 (2016)


Article DOI: 10.1016/j.bmc.2016.09.071
BindingDB Entry DOI: 10.7270/Q29C70D7
More data for this
Ligand-Target Pair