BDBM50195584 1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (4-hydroxyphenyl)amide::CHEMBL438475

SMILES: Oc1c(C(=O)c2ccc(O)cc2)c(=O)n(-c2ccc(Cl)cc2)n1-c1ccc(Cl)cc1

InChI Key: InChIKey=FMGQPLOCNHWRKJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195584   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MurB (E. coli) (Escherichia coli K-12 (Enterobacteria))	BDBM50195584 (1,2-bis(4-chlorophenyl)-5-hydroxy-3-oxo-2,3-dihydr...) Show SMILES Oc1c(C(=O)c2ccc(O)cc2)c(=O)n(-c2ccc(Cl)cc2)n1-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H14Cl2N2O4/c23-14-3-7-16(8-4-14)25-21(29)19(20(28)13-1-11-18(27)12-2-13)22(30)26(25)17-9-5-15(24)6-10-17/h1-12,27,29H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Curated by ChEMBL					Assay Description Inhibition of MurB activity				J Med Chem 49: 6027-36 (2006) Article DOI: 10.1021/jm060499t BindingDB Entry DOI: 10.7270/Q22V2FRV
					More data for this Ligand-Target Pair