BDBM50195597 2-amino-1,5-dihydro-7-[[N,N-bis-[2-(hydroxy)ethyl]amino]methyl]-4H-pyrrolo[3,2-d]pyrimidin-4-one diacetate

SMILES: Nc1nc2c(CN(CCO)CCO)c[nH]c2c(=O)[nH]1

InChI Key: InChIKey=RQFCXZOEUWEVIX-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50195597 (2-amino-1,5-dihydro-7-[[N,N-bis-[2-(hydroxy)ethyl]...) Show SMILES Nc1nc2c(CN(CCO)CCO)c[nH]c2c(=O)[nH]1 Show InChI InChI=1S/C11H17N5O3/c12-11-14-8-7(5-13-9(8)10(19)15-11)6-16(1-3-17)2-4-18/h5,13,17-18H,1-4,6H2,(H3,12,14,15,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human PNP activity				J Med Chem 49: 6037-45 (2006) Article DOI: 10.1021/jm060547+ BindingDB Entry DOI: 10.7270/Q2NV9K11
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50195597 (2-amino-1,5-dihydro-7-[[N,N-bis-[2-(hydroxy)ethyl]...) Show SMILES Nc1nc2c(CN(CCO)CCO)c[nH]c2c(=O)[nH]1 Show InChI InChI=1S/C11H17N5O3/c12-11-14-8-7(5-13-9(8)10(19)15-11)6-16(1-3-17)2-4-18/h5,13,17-18H,1-4,6H2,(H3,12,14,15,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human PNP activity				J Med Chem 49: 6037-45 (2006) Article DOI: 10.1021/jm060547+ BindingDB Entry DOI: 10.7270/Q2NV9K11
					More data for this Ligand-Target Pair