BDBM50195706 3-(5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-(propoxycarbonyl)-1,2,3,4-tetrahydroisoquinolin-8-yl)propanoic acid::CHEMBL376460

SMILES: CCCOC(=O)N1CCc2c(OCCc3nc(oc3C)-c3ccccc3)ccc(CCC(O)=O)c2C1

InChI Key: InChIKey=WVKGGZXCUUYLIT-UHFFFAOYSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50195706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50195706 (3-(5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-(p...) Show SMILES CCCOC(=O)N1CCc2c(OCCc3nc(oc3C)-c3ccccc3)ccc(CCC(O)=O)c2C1 Show InChI InChI=1S/C28H32N2O6/c1-3-16-35-28(33)30-15-13-22-23(18-30)20(10-12-26(31)32)9-11-25(22)34-17-14-24-19(2)36-27(29-24)21-7-5-4-6-8-21/h4-9,11H,3,10,12-18H2,1-2H3,(H,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	561	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of tritium labeled ligand from human PPARalpha by SPA assay				Bioorg Med Chem Lett 16: 6293-7 (2006) Article DOI: 10.1016/j.bmcl.2006.09.028 BindingDB Entry DOI: 10.7270/Q23R0TNK
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50195706 (3-(5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-(p...) Show SMILES CCCOC(=O)N1CCc2c(OCCc3nc(oc3C)-c3ccccc3)ccc(CCC(O)=O)c2C1 Show InChI InChI=1S/C28H32N2O6/c1-3-16-35-28(33)30-15-13-22-23(18-30)20(10-12-26(31)32)9-11-25(22)34-17-14-24-19(2)36-27(29-24)21-7-5-4-6-8-21/h4-9,11H,3,10,12-18H2,1-2H3,(H,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of tritium labeled ligand from human PPARalpha by SPA assay				Bioorg Med Chem Lett 16: 6293-7 (2006) Article DOI: 10.1016/j.bmcl.2006.09.028 BindingDB Entry DOI: 10.7270/Q23R0TNK
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50195706 (3-(5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-(p...) Show SMILES CCCOC(=O)N1CCc2c(OCCc3nc(oc3C)-c3ccccc3)ccc(CCC(O)=O)c2C1 Show InChI InChI=1S/C28H32N2O6/c1-3-16-35-28(33)30-15-13-22-23(18-30)20(10-12-26(31)32)9-11-25(22)34-17-14-24-19(2)36-27(29-24)21-7-5-4-6-8-21/h4-9,11H,3,10,12-18H2,1-2H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of tritium labeled ligand from human PPARgamma by SPA assay				Bioorg Med Chem Lett 16: 6293-7 (2006) Article DOI: 10.1016/j.bmcl.2006.09.028 BindingDB Entry DOI: 10.7270/Q23R0TNK
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50195706 (3-(5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-(p...) Show SMILES CCCOC(=O)N1CCc2c(OCCc3nc(oc3C)-c3ccccc3)ccc(CCC(O)=O)c2C1 Show InChI InChI=1S/C28H32N2O6/c1-3-16-35-28(33)30-15-13-22-23(18-30)20(10-12-26(31)32)9-11-25(22)34-17-14-24-19(2)36-27(29-24)21-7-5-4-6-8-21/h4-9,11H,3,10,12-18H2,1-2H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of tritium labeled ligand from human PPARgamma by SPA assay				Bioorg Med Chem Lett 16: 6293-7 (2006) Article DOI: 10.1016/j.bmcl.2006.09.028 BindingDB Entry DOI: 10.7270/Q23R0TNK
					More data for this Ligand-Target Pair